Interoperability Resources

Interoperability Resources

This page contains links to resources to learn more about healthcare interoperability standards, U.S. policies and public health use cases. Healthcare interoperability standards and policies are rapidly changing and updates to this page will be made as needed.

    • Certification of Electronic Health Record exchange APIs requires use of USCDI version 2; use of version 3 will be required as of December 31, 2025. Current adoption by EHRs can be found here: adoption by EHRs.
    • Timeline – initial input closes September; version for public comment February – April; publishes every July.
    • NOTE: The HL7 US Core Implementation Guide is released about one year after USCDI.
  • USCDI+ is not required for EHR certification but includes specialized use cases, such as public health. You can create an account to add comments.
    • Intended to fill the gaps for quality, public health, providers, behavioral health, etc.
    • Much more flexible – but on an annual time frame to make it easier for vendors.

    US Core Implementation Guide (HL7) defines the minimum constraints on FHIR to implement USCDI. The latest version can be found here: HL7.FHIR.US.CORE\Home – FHIR v4.0.1. It provides more specificity and guidance than USCDI. Many other HL7 standards are built off of the US Core Implementation Guide. Note: The update cycles for USCDI and US Core are different, so the standards are not always 100% aligned.

  • US Public Health Profiles Library (HL7) is a collection of reusable architecture and content profiles representing common public health concepts and patterns. It is intended as a complement to the US Core Implementation Guide to meet reporting requirements for public health. The latest version can be found here: Home Page – US Public Health Profiles Library v1.0.0.
  • Minimal Common Oncology Data Elements (mCODE): HL7.FHIR.US.MCODE\Home – FHIR v4.0.1. Uses ~30 FHIR profiles that cover patient, disease, health assessment, genomics, cancer treatment and outcomes. mCODE defines relationships between the profiles and is intended to be used in implementation guides that further specify what information is required for a patient for different uses.
  • Making Electronic Data More Available for Research and Public Health (MedMorph) has two separate Implementation Guides of interest:
  • Cancer Pathology Data Sharing Implementation Guide provides HL7 FHIR resources to define standards for cancer pathology information exchange from a hospital or facility-based laboratory information system to a hospital or facility-based electronic health record (EHR) system. See HL7.FHIR.US.CANCER-REPORTING\Home Page – FHIR v4.0.1.

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